Total Cycles
155
Reported 2022
Medical Disclaimer: This data is for informational purposes only. Success rates are influenced by patient age, diagnosis, and treatment type. Do not use this data alone to choose a fertility clinic. Consult a board-certified reproductive endocrinologist.
GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute reported a 16.4% overall live-birth rate across 155 ART cycles in San Juan, Puerto Rico (CDC NASS 2022).
Clinic verdict · CDC NASS 2022
GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute's IVF live-birth rate for patients under 35 is 26.3%, 22 points below the national average of 48%. Compare it across age groups and against the state below, and remember age is the strongest driver of IVF success.
Overall CDC live-birth-rate band, 406 reporting clinics
Total Cycles
155
Reported 2022
Overall Success Rate
16.4%
Live births per cycle
+1.9pp vs PR avg
Rate Under 35
26.3%
Peak fertility cohort
Single Embryo Transfer
22.8%
ASRM-aligned safety metric
Single-embryo-transfer rate is an ASRM-aligned safety metric, higher SET reduces multi-pregnancy and OHSS risk.
Share of transfers using one embryo only
Using own eggs (fresh + frozen cycles). The CDC reports patients over 40 in two separate brackets, 41–42 and 43+, shown here individually rather than combined.
Success rate = live births per ART cycle started. Source: CDC NASS 2022.
GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute reported cycle outcomes to the CDC National ART Surveillance System for the 2022 reporting year, with 3 years of cumulative reporting history. The clinic performed 155 total ART cycles, split between 124 fresh and 31 frozen embryo transfer cycles. The overall success rate, live births per cycle started, was 16.4%. That is 1.9 percentage points above the Puerto Rico state average of 14.5%.
Age remains the dominant variable in IVF outcomes. At GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute, patients under 35 saw a 26.3% success rate, compared with 16.0% for ages 35–37 and 9.7% for ages 38–40. Ages 41–42 reported N/A, and ages 43+ reported N/A. Single embryo transfer (SET) was used in 22.8% of cycles, a metric ASRM associates with lower multi-pregnancy rates.
Service availability also affects which clinics fit which patients. GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute does not report donor egg services in the latest NASS filing, and gestational carrier services are not listed in the latest NASS filing. These services matter for patients with diminished ovarian reserve, same-sex couples, or medical conditions that preclude carrying a pregnancy. Every figure above is a public federal disclosure, not editorial commentary, PlainFertility is not affiliated with GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute or the CDC, and these statistics are not a substitute for an evaluation by a board-certified reproductive endocrinologist who can assess your individual diagnosis, history, and treatment options.
Read these figures as a starting point, not a verdict. The CDC reports live births per intended egg retrieval, so the percentages already account for cycles that never reached embryo transfer, a more conservative measure than the per-transfer pregnancy rates clinics sometimes advertise. Group results describe what happened for past patients; they cannot predict an individual outcome, which depends on diagnosis, ovarian reserve, sperm quality, embryo genetics, and the protocol a physician recommends. A single reporting year can swing for lower-volume clinics, so cumulative multi-year results and a candid consultation carry more weight than any one published number.
| Year | Total Cycles | Overall | Under 35 | 35–37 | 38–40 | 41–42 |
|---|---|---|---|---|---|---|
| 2022 | 155 | 16.4% | 26.3% | 16.0% | 9.7% | N/A |
| 2021 | 170 | 15.7% | 18.2% | N/A | 10.7% | N/A |
| 2020 | 129 | N/A | N/A | N/A | N/A | N/A |
GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute reports an overall IVF success rate of 16.4% across 155 reported cycles. Rates by age group vary, patients under 35 generally see higher success rates.
IVF success rates depend on patient age, diagnosis, embryo type, and treatment protocol. A clinic with a lower success rate may treat more complex cases. Always consult a board-certified reproductive endocrinologist who can evaluate your individual situation.
All data is sourced from the CDC's National ART Surveillance System (NASS), which requires all ART clinics in the US to report their cycle outcomes annually under the Fertility Clinic Success Rate and Certification Act of 1992.
Fresh cycles use embryos that have not been frozen, eggs are retrieved, fertilized, and transferred within the same treatment cycle. Frozen cycles use previously cryopreserved embryos. GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute reported 124 fresh cycles and 31 frozen cycles. Many clinics now favor frozen embryo transfers (FET) due to improved vitrification technology and comparable or higher success rates.
Single embryo transfer percentage indicates how often a clinic transfers just one embryo per cycle rather than multiple embryos. A higher SET rate generally reflects adherence to current ASRM guidelines aimed at reducing multiple pregnancies. GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute reports a SET rate of 22.8%. Higher SET rates typically mean fewer twins and triplets, which reduces pregnancy complications.
GREFI, Gynecology, Reproductive Endocrinology & Fertility Institute does not currently list donor egg services and does not currently list gestational carrier services per the latest CDC NASS report. Contact the clinic directly to confirm current service availability and discuss whether these options are appropriate for your treatment plan.
Data source: CDC National ART Surveillance System (NASS). PlainFertility is not affiliated with the CDC or this clinic.
Read our methodology - how this data is sourced, computed, and verified.
Every figure on PlainFertility is rendered directly from CDC National ART Surveillance System source data, no number is typed in by an editor. This page draws directly on CDC National ART Surveillance System source data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.